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Increasing Preoperative Cognitive Reserve to Prevent Postoperative Cognitive Dysfunction in Cardiac Surgical Patients

NCT04493996 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 100

Last updated 2026-02-17

No results posted yet for this study

Summary

Postoperative delirium (POD) and postoperative cognitive decline (POCD) can be observed after cardiosurgical interventions. Taken together, these postoperative neurocognitive dysfunctions contribute to increased morbidity and mortality and higher economic costs. Preoperative risk factors of postoperative neurocognitive dysfunctions, such as decreased neuropsychometric performance or decreased cognitive daily activities, can be interpreted as reduced cognitive reserve. The aim of this study is to build up cognitive reserves to protect against the development of POD and POCD through preoperative, home-based, cognitive training.

Conditions

  • Postoperative Cognitive Decline
  • Postoperative Delirium
  • Postoperative Cognitive Dysfunction

Interventions

BEHAVIORAL

Cognitive training

The cognitive training involves a standardized, paper-and-pencil-based cognitive training that will be performed by the patients at home for approximately 40 minutes per day over a preoperative period of 2-3 weeks

Sponsors & Collaborators

  • Heart and Brain Research Group, Germany

    lead OTHER

Principal Investigators

  • Marius Butz, Dipl.-Psych. · Department of Cardiac Surgery, Kerckhoff Clinic Bad Nauheim

  • Martin Jünemann, Dr.med,M.Sc. · Clinic for Neurology, University Hospital Gießen

  • Tibo Gerriets, Prof.Dr.med. · Department of Neurology, Gesundheitszentrum Wetterau

  • Markus Schönburg, Prof.Dr.med. · Department of Cardiac Surgery, Kerckhoff Clinic Bad Nauheim

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-08-14
Primary Completion
2026-03-31
Completion
2026-03-31

Countries

  • Germany

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04493996 on ClinicalTrials.gov