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Safety of Ibuprofen After Major Orthopaedic Surgeries

NCT05575700 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 2904

Last updated 2025-12-19

No results posted yet for this study

Summary

Safety of an eight-day treatment with ibuprofen after primary hip and knee arthroplasties.

Conditions

  • Pain, Acute
  • Hip Arthropathy
  • Knee Arthropathy
  • Safety Issues
  • Analgesia
  • Analgesic Adverse Reaction
  • Postoperative Pain
  • Postoperative Complications

Interventions

DRUG

Ibuprofen

400 mg tablet three times daily

DRUG

Placebo

tablet three times daily

Sponsors & Collaborators

  • Naestved Hospital

    lead OTHER

Principal Investigators

  • Ole Mathiesen, Professor · Zealand University Hospital

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-04-17
Primary Completion
2025-08-19
Completion
2025-08-19

Countries

  • Denmark

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05575700 on ClinicalTrials.gov