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Quantification of Factors Influencing Endothelial Damage During Phacoemulsification

NCT05529485 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 121

Last updated 2022-09-10

No results posted yet for this study

Summary

The aim of this study is to determine the principal factors that influence endothelial cell loss three month post cataract surgery.

Methods: Multi center observational Cohort study, inclusion period from 12/01/2022 to 10/06/2022. One hundred and seventy-five eyes of hundred and four patients who have appointment for cataract surgical indication were included. The percentage of corneal endothelial cell loss was quantified using specular microscopy before and 3 months after the surgery.

14 variables (pre-operative and intra-operative) that could be associated to endothelial cell injury were selected.

A bivariate analysis of relationship between these factors and endothelial cell loss at 3 months was performed by simple linear regression (Wilcoxon and Fischer tests). Multivariate analysis was performed by multiple linear regression in order to identify the factors independently related to endothelial cell loss.

Conditions

  • Endothelial Cell Loss, Corneal
  • Cataract
  • Phacoemulsification

Interventions

PROCEDURE

Cataract surgery by phacoemulsification

Cataract surgery by phacoemulsification

Sponsors & Collaborators

  • Centre Hospitalier Régional Metz-Thionville

    lead OTHER

Principal Investigators

  • Jean Marc Perone · CHR Metz Thionville Hopital de Mercy

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-01-12
Primary Completion
2022-08-01
Completion
2022-08-01

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05529485 on ClinicalTrials.gov