Dysautonomia and Systemic Interactions in Traumatic Brain Injury

NCT05515640 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 24

Last updated 2024-03-08

No results posted yet for this study

Summary

Following brain injury, complex interactions between the nervous system and other organs are frequently encountered. Systemic effects may be induced by dysregulation of the hypothalamic-pituitary-adrenal axis and the autonomic nervous system. This observational study will investigate the link between clinical, physiological and biochemical expressions of dysautonomic reactions and physiological stress, and their relations to sympathetic activation in traumatic brain injury patients treated in the neurointensive care unit.

Conditions

Sponsors & Collaborators

  • Region Stockholm

    collaborator OTHER_GOV
  • Eurostars

    collaborator OTHER
  • Vinnova

    collaborator OTHER_GOV
  • Karolinska University Hospital

    lead OTHER

Principal Investigators

  • David W Nelson, M.D., Ph.D. · Karolinska University Hospital

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-08-01
Primary Completion
2024-06-30
Completion
2024-06-30

Countries

  • Sweden

Study Locations

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Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05515640 on ClinicalTrials.gov