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Supplementation With Altha-aminoacids and Systemiec Inflammatory Response in Long-distance Runners.

NCT05510440 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 60

Last updated 2023-01-04

No results posted yet for this study

Summary

It is also noteworthy that the imbalance between the production, supply and elimination of especially α-amino acids may contribute to the intensification of the inflammatory response and the subsequent burden of the renal tubules, which may result in damage and developing chronic renal failure.

Among the many amino acids used in sports, arginine and its metabolites deserve special attention. The role of arginine appears to increase in specific physiological states associated with disease, injury or significant strain on the body, leading to an increase in the rate of catabolic transformation.

Arginine plays a significant role in protein biosynthesis and detoxification processes related to ammonia removal and urea formation .

Conditions

  • Exercise Myoglobinuria
  • Citrulline; Metabolic Disorder
  • Iron Metabolism Disorders
  • Inflammatory Response

Interventions

DIETARY_SUPPLEMENT

Alpha-amino acid derivatives

Alpha-amino acid derivatives mainly citrulline will be used as a supplement to reduce kidneys and other internal organs damage

Sponsors & Collaborators

  • Gdansk University of Physical Education and Sport

    collaborator OTHER

  • Medical University of Gdansk

    lead OTHER

Principal Investigators

  • Jędrzej Antosiewicz · Medical University of Gdańsk, Poland

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
21 Years
Max Age
40 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-03-01
Primary Completion
2023-05-01
Completion
2023-11-30

Countries

  • Poland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05510440 on ClinicalTrials.gov