Efficacy of Trypsin-Chymotrypsin On Post-operative Pain After Single Visit Root Canal Treatment
NCT05479747 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 60
Last updated 2024-03-01
Summary
Achieving effective pain control after endodontic treatment is still a disruptive event to all the clinicians. There is a knowledge gap regarding the effect of protease on postoperative pain following root canal treatment, therefore, the efficacy of Trypsin-Chymotrypsin on post endodontic pain was evaluated clinically in a randomized triple-blind trial.
Conditions
- Effect of Drug
Interventions
- DRUG
-
post operative analgesics
post-operative pain killer
Sponsors & Collaborators
-
Ain Shams University
lead OTHER
Principal Investigators
-
Ahmed A Hashem, PHD · Head of endodontic department Faculty of dentistry Ain Shams University, cairo,Egypt
-
Tariq Y Abdel Rahman, PHD · Lecturer, Endodontic Department, Faculty of Dentistry, Ain Shams University
-
Alaa A Abd El Sattar, Master · Faculty of Dentistry, Ain Shams University
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- TRIPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 40 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2021-06-01
- Primary Completion
- 2021-12-31
- Completion
- 2021-12-31
Countries
- Egypt
Study Locations
More Related Trials
-
Comparing Trypsin-Chymotrypsin and Naproxen Sodium for Post-endodontic Treatment Pain
NCT06562816 ·Status: RECRUITING ·Phase: PHASE4
-
Effect of Submucosal Cryotherapy on Postoperative Endodontic Pain
NCT06090500 ·Status: COMPLETED ·Phase: NA
-
The Effect of Anti-inflammatory Cryoagent on the Level of Postoperative Pain in Patients With Symptomatic Irreversible Pulpitis and Apical Periodontitis.
NCT06584188 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Effect of Cryotherapy on Postoperative Pain
NCT03716635 ·Status: UNKNOWN ·Phase: NA
-
Ketorolac Irrigant on Post Operative Pain
NCT04319549 ·Status: UNKNOWN ·Phase: NA
-
Occlusal Reduction Effect on Postendodontic Pain
NCT04186897 ·Status: COMPLETED ·Phase: NA
-
Effect of Triple Antibiotic Paste as an Intracanal Medication With an Anti-Inflammatory Drug on Post-operative Pain.
NCT02907489 ·Status: COMPLETED ·Phase: PHASE1
-
The Effect of Intra Oral Cryotherapy in Patients With Symptomatic Apical Periodontitis
NCT06082479 ·Status: COMPLETED ·Phase: NA
-
Influence of Apical Patency Concept Upon Postoperative Pain After Root Canal Treatment
NCT05170477 ·Status: COMPLETED ·Phase: NA
-
Effect of Different Modalities of Cryotherapy on Post-Operative Pain in Patients With Symptomatic Irreversible Pulpitis
NCT06304259 ·Status: COMPLETED ·Phase: NA
-
Clinical and Biochemical Effects Of Cryotherapy Protocols On Mandibular Premolars With Symptomatic Apical Periodontitis
NCT07138365 ·Status: COMPLETED ·Phase: NA
-
Comparison of a Prophylactic Intraligamentary Injection of Piroxicam Versus Mepecaine of Post-endodontic Pain
NCT03006107 ·Status: UNKNOWN ·Phase: NA
-
Effectiveness of Cryotherapy on Endodontic Pain
NCT06785753 ·Status: RECRUITING ·Phase: PHASE2
-
Effect of Removal of Double Antibiotic Paste on Post Operative Pain
NCT04327453 ·Status: UNKNOWN ·Phase: NA
-
Bacterial Reduction and Post Operative Endodontic-pain Using Different Kinematics
NCT04990115 ·Status: COMPLETED ·Phase: NA
-
Effects of Intracanal Cryotherapy on Endodontic Postoperative Pain
NCT05611736 ·Status: COMPLETED ·Phase: NA
-
The Impact Of Different Final Irrigation Activation Techniques On Postoperative Pain
NCT06501703 ·Status: COMPLETED ·Phase: NA
-
Effect of NanoChitosan Impregnated Calcium Hydroxide as an Intracanal Medication on Postoperative Pain Intensity and Bacterial Load Reduction
NCT06253247 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
The Effect of Commercial and Medical Grade Sodium Hypochlorite on Post Endodontic Pain
NCT07248189 ·Status: COMPLETED ·Phase: NA
-
Intraoral Cryotherapy in Root Canal Retreatment
NCT05091554 ·Status: COMPLETED ·Phase: NA
-
Effect of Calcium Hypochlorite Versus Sodium Hypochlorite as Root Canal Irrigants on Postoperative Pain and Bacterial Reduction in Mandibular Premolars With Necrotic Pulps. .
NCT06509295 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Effect Of XP Endo Finisher Versus Ultrasonic Activated Irrigation On Post-operative Pain In Endodontic Treatment of Symptomatic Irreversible Pulpitis
NCT03096587 ·Status: UNKNOWN ·Phase: NA
-
Postoperative Pain Evaluation of Mineral Trioxide Aggregate and Propolis After Pulpotomy in Carious Primary Molars
NCT03580135 ·Status: UNKNOWN ·Phase: PHASE2
-
Effect of Apical Patency and Local Corticosteroid on Pain and Neuropeptides Release in Patients With Symptomatic Irreversible Pulpitis: A Randomized Clinical Trial
NCT06457828 ·Status: RECRUITING ·Phase: NA
-
Healing Potentiality of Trypsin and Alpha Chemo Trypsin in Mandibular Molars With Chronic Apical Abscess
NCT06164509 ·Status: NOT_YET_RECRUITING ·Phase: PHASE4