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Spinal Cord Stimulation and Training

NCT05472584 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 120

Last updated 2026-04-02

No results posted yet for this study

Summary

This study will help the investigators better understand the changes in short-term excitability and long-term plasticity of corticospinal, reticulospinal and spinal neural circuits and how the changes impact the improvements of spinal cord stimulation (SCS) mediated motor function.

Conditions

  • Spinal Cord Injuries

Interventions

OTHER

Electrophysiology assessment - corticospinal tract

Kinematics and cortical spinal motor excitability

OTHER

Electrophysiology assessment - reticulospinal tract

Kinematics and reticular spinal motor excitability

OTHER

Electrophysiology assessment - spinal motoneuron

Kinematics and spinal motoneuron excitability

OTHER

Activity-based training

Motor task

OTHER

Transcutaneous spinal cord stimulation

Non-invasive spinal cord stimulation

Sponsors & Collaborators

  • Washington University School of Medicine

    lead OTHER

Principal Investigators

  • Ismael Seanez, PhD · Washington University School of Medicine

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
16 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-07-21
Primary Completion
2027-08-31
Completion
2027-08-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05472584 on ClinicalTrials.gov