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Neuroplasticity After Spinal Cord Injury

NCT02446210 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 514

Last updated 2021-05-25

No results posted yet for this study

Summary

The long-term goal is to acquire scientific knowledge that can be used to develop mechanistic-driven intervention strategies aiming at restoring upper and lower-limb motor function in individuals with cervical or thoracic spinal cord injury (SCI). The proposed project will examine cortical, corticospinal, and spinal contribution to bilateral hand and arm muscle activity during bilateral movements and spinal contributions to lower limb muscle activity. By comparing changes in different sites within the Central Nervous System (CNS), the investigators may also identify key mechanisms that might be differentially affected by the injury, plasticity, and training.

Conditions

  • Spinal Cord Injury

Interventions

DEVICE

Magstim 200

Transcranial Magnetic Stimulation

DEVICE

Digitimer electrical stimulator

Transcranial Magnetic Stimulation paired with Electrical Peripheral Nerve Stimulation

Sponsors & Collaborators

  • National Institute of Neurological Disorders and Stroke (NINDS)

    collaborator NIH

  • Shirley Ryan AbilityLab

    lead OTHER

Principal Investigators

  • Monica A Perez, PhD, PT · Shirley Ryan AbilityLab

Study Design

Allocation
RANDOMIZED
Purpose
DIAGNOSTIC
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-01-28
Primary Completion
2022-01-27
Completion
2023-01-27

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02446210 on ClinicalTrials.gov