Effect of Low-dose Versus Standard-dose Iron Supplementation on the Gut Microbiome
NCT05467423 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30
Last updated 2023-12-29
Summary
Iron deficiency is a common problem that is often treated with the administration of oral iron.
Most of the iron is not absorbed and remains in the intestine, where it influences the balance of gut bacteria.
This influence is usually undesirable and should be kept as small as possible. With lower iron doses, the amount of unabsorbed iron is smaller and therefore a smaller change in the intestinal bacteria composition is to be expected.
Conditions
- Iron Deficiency (Without Anemia)
Interventions
- DIETARY_SUPPLEMENT
-
Iron
4 weeks of daily oral iron therapy. The subjects administer the therapy themselves.
Sponsors & Collaborators
-
University of Zurich
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 50 Years
- Sex
- FEMALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2023-01-04
- Primary Completion
- 2023-04-30
- Completion
- 2023-09-30
Countries
- Switzerland
Study Locations
More Related Trials
-
The Effect of Different Prebiotics on Iron Absorption From High Dose Iron Supplements
NCT04194255 ·Status: COMPLETED ·Phase: NA
-
The Efficacy of Minayo Iron-rich Yeast Drink With SOD on Female Nutritional Anemia, Skin Condition and Qi-blood Deficiency Syndrome
NCT06066151 ·Status: COMPLETED ·Phase: NA
-
Assessing the Immediate Increase in Serum Ferritin After Oral Iron Doses
NCT06657677 ·Status: COMPLETED ·Phase: NA
-
Effect of Iron Supplements on the Growth of Enteric Pathogens
NCT05762380 ·Status: COMPLETED ·Phase: NA
-
Determination of Iron Absorption Mechanism From Ferrous Fumarate With GOS
NCT03996421 ·Status: COMPLETED ·Phase: NA
-
Heme and Non-heme Iron Intakes, Gut Microbiota, and Influence on Host Iron Absorption
NCT06146608 ·Status: RECRUITING
-
Iron Absorption From GDS Capsules
NCT01874496 ·Status: COMPLETED ·Phase: NA
-
Fermented Iron-rich Supplement in Reducing Anemia
NCT02037724 ·Status: UNKNOWN ·Phase: PHASE2
-
Effects of Oral Iron Supplementation on Vaccine Response in Iron Deficient Kenyan Women
NCT05919472 ·Status: COMPLETED ·Phase: NA
-
The Effect of Zinc on Iron Bioavailability From Fortified Extruded Rice Fortified With Ferric Pyrophosphate
NCT02255942 ·Status: COMPLETED ·Phase: NA
-
Determination of a Dose-dependent Effect of GOS on Iron Absorption, and Addition of Vitamin C
NCT03762148 ·Status: COMPLETED ·Phase: NA
-
The Optimization of Bioavailability From Iron Supplements: Study 1
NCT02175888 ·Status: COMPLETED ·Phase: NA
-
Iron Isotope Study of an Iron Fatty Acid Complex
NCT03895424 ·Status: COMPLETED ·Phase: NA
-
Iron Supplementation and Side Effects
NCT04018300 ·Status: COMPLETED ·Phase: NA
-
Can the Reduction of Iron Availability Caused by Tea Consumption Change the Gut Microbiota Composition and Disrupt Host Body-iron Status
NCT05019573 ·Status: UNKNOWN ·Phase: NA
-
Impact of Zinc Supplementation on Mortality and Hospitalizations in Children Aged 1 Months to 23 Months
NCT00269542 ·Status: COMPLETED ·Phase: NA
-
Optimizing Iron Status While Minimizing Morbidity in HIV-infected Ugandan Children
NCT03596996 ·Status: COMPLETED ·Phase: NA
-
Iron Absorption From a Micronutrient Powder Containing Galacto-oligosaccharides (GOS)
NCT02666417 ·Status: COMPLETED ·Phase: NA
-
Effect of Double Fortification (Iron and Zinc) in Synbiotic Milk to Under 5 Years Stunted Children Growth
NCT03495401 ·Status: UNKNOWN ·Phase: NA
-
Probing the Synergistic Effect of Pre-Biotics & Iron Fortificants in Anemic Subjects
NCT03894449 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Impact of Sprinkles on Infectious Morbidity When Moderate to Severe Pediatric Malnutrition Is Highly Prevalent
NCT00530374 ·Status: COMPLETED ·Phase: PHASE3
-
Safety of Various Mode of Delivery of Iron Supplement on Iron Toxicity Markers in Preschool Children
NCT00980421 ·Status: UNKNOWN ·Phase: PHASE3
-
Comparison of Nutritional Information With Iron-succinate Supplementation in Healthy Women
NCT06648018 ·Status: ENROLLING_BY_INVITATION ·Phase: NA
-
Absorption, Stable Isotope Appearance and Non-transferrin-bound Iron (NTBI) Profile From NaFeEDTA and Ferrous Sulphate
NCT01053442 ·Status: COMPLETED ·Phase: NA
-
A Double-blind, Double-dummy, Parallel, Active-controlled, Randomized Trial to Evaluate Efficacy & Safety in Anemia Subjects
NCT01425463 ·Status: COMPLETED ·Phase: PHASE3