Nasal Desmopressin Versus Oral Bisoprolol for Controlling Bleeding During Endoscopic Sinus Surgery
NCT05430048 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 100
Last updated 2022-11-10
Summary
Functional endoscopic sinus surgery (FESS) is well established for treatment of chronic rhinosinusitis and nasal polyps. Masking of the surgical field can lead to severe complication as tissue injury, increase post-operative adhesions and scarring and even severe orbital and brain injury In the current study we will investigate the effect of nasal desmopressin versus oral bisoprolol for controlling bleeding and improving surgical field clarity during functional endoscopic sinus surgery
Conditions
Interventions
- DRUG
-
nasal Desmopressin
compare the effect of nasal desmopressin versus oral bisoprolol for controlling bleeding and improving surgical field clarity during functional endoscopic sinus surgery.
Sponsors & Collaborators
-
Zagazig University
lead OTHER_GOV
Principal Investigators
-
Heba M Fathi · Zagazig University
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- TRIPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 21 Years
- Max Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-07-01
- Primary Completion
- 2022-10-30
- Completion
- 2022-11-05
Countries
- Egypt
Study Locations
More Related Trials
-
The Role of Budesonide Intrapolyp Injection in CRSwNP
NCT05474924 ·Status: UNKNOWN ·Phase: PHASE4
-
Effects of Lidocaine Infusion on Quality of Recovery and Agitation After Functional Endoscopic Sinus Surgery
NCT04472689 ·Status: UNKNOWN ·Phase: NA
-
Comparing Blood Loss and Visualization After the Preoperative Use of Topical 0.05% Oxymetazoline Versus 1:1000 Epinephrine Prior to Endoscopic Sinus Surgery
NCT03228914 ·Status: COMPLETED ·Phase: PHASE4
-
The Role of Budesonide Intrapolyp Injection in the Management of Type 2 Chronic Rhinosinusitis
NCT05931744 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
The Effect of Preoperative Oral Prednisone on the Operative Field During Nasal Polypectomy.
NCT00440219 ·Status: COMPLETED ·Phase: PHASE3
-
Results of Endoscopic Sinus Surgery in Management of Ophthalmological Complications of Chronic Rhino Sinusitis
NCT04617223 ·Status: COMPLETED ·Phase: NA
-
Comparison of Nasal Steroids After FESS in CRSwNP
NCT02194062 ·Status: COMPLETED ·Phase: NA
-
Effect of Hot Saline Irrigation on the Operative Field During Endoscopic Sinus Surgery
NCT06343493 ·Status: COMPLETED ·Phase: NA
-
Radiologic Scoring of Patients With Chronic Sinusitis and Nasal Polyps
NCT03174483 ·Status: UNKNOWN ·Phase: NA
-
Nasal Packing Duration and Development of Pharyngitis After Septorhinoplasty Surgery
NCT06291402 ·Status: RECRUITING
-
Topical Irrigation Therapy for CRS
NCT02630472 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Impact of Posterior Nasal Neurectomy With Functional Endoscopic Sinus Surgery for Chronic Rhinosinusitis With Nasal Polyposis:A Comparative Study
NCT04105361 ·Status: UNKNOWN ·Phase: NA
-
Endoscopic Frontal Sinus Surgery Draf III in Moderate to Severe Eosinophilic Chronic Rhinosinusitis With Polyps
NCT05979662 ·Status: UNKNOWN ·Phase: NA
-
Effect of Full-House ESS With Nasopharyngeal Lymphoid Tissue Ablation on Nasal Polyps
NCT07245329 ·Status: RECRUITING ·Phase: NA
-
Analysis of Hemostatic Agents Compared to Physiologic Hemostasis
NCT03068728 ·Status: COMPLETED ·Phase: NA
-
Rhinological Outcomes in Endonasal Pituitary Surgery
NCT01504399 ·Status: COMPLETED
-
Impact of COVID-19 on Sinus Augmentation Surgery
NCT05960136 ·Status: COMPLETED ·Phase: NA
-
The Role of the Submucosal Conchoplasty Technique in Improving the Postoperative Middle Meatus Outcome After ESS
NCT05930132 ·Status: COMPLETED ·Phase: NA
-
Are NSAIDs Effective Enough for Postoperative Pain Control After Functional Endoscopic Sinus Surgery and Septoplasty
NCT03605914 ·Status: COMPLETED ·Phase: PHASE4
-
Prospective Hemodynamic and Pharmacokinetic Analysis of Oxymetazoline Absorption
NCT02453841 ·Status: COMPLETED ·Phase: NA
-
Pre-operative Steroids in CRSsP
NCT05095961 ·Status: WITHDRAWN ·Phase: PHASE2/PHASE3
-
Intranasal Injection Versus Topical Administration of Epinephrin During Endoscopic Sinus Surgery
NCT01075581 ·Status: UNKNOWN ·Phase: NA
-
Utility of Indocyanine Green Fluorescence in Endoscopic Sinonasal and Skull Base Surgery
NCT04374448 ·Status: UNKNOWN ·Phase: NA
-
Safety and Performance of the Steroid-Releasing S8 Sinus Implant
NCT01894503 ·Status: COMPLETED ·Phase: PHASE2
-
Treatment of Post-Operative Sinonasal Polyposis With Topical Furosemide
NCT03362515 ·Status: TERMINATED ·Phase: PHASE2