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Functional Endoscopic Sinus Surgery Study

NCT03970655 · Status: ACTIVE_NOT_RECRUITING · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 80

Last updated 2026-01-27

No results posted yet for this study

Summary

The aim of this study is to evaluate the effect of the addition of epinephrine to bilateral real time ultrasound guided pterygopalatine ganglion blocks on intra-operative bleeding and blood loss during functional endoscopic sinus surgery (FESS).

Conditions

  • Chronic Rhinosinusitis (Diagnosis)

Interventions

DRUG

Bupivacaine or Ropivacaine with epinephrine plus dexamethasone - Group 2

Group 2 will receive 4 ml of 0.5% Bupivacaine or Ropivacaine with epinephrine in the RIGHT pterygopalatine fossa

DRUG

Bupivacaine or Ropivacaine with epinephrine plus dexamethasone - Group 1

Group 1 will receive 4 ml of 0.5% Bupivacaine or Ropivacaine with epinephrine in the LEFT pterygopalatine fossa

Sponsors & Collaborators

  • University of Florida

    lead OTHER

Principal Investigators

  • Cameron R Smith · University of Florida

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-09-25
Primary Completion
2026-01-23
Completion
2027-01-23
FDA Drug
Yes

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03970655 on ClinicalTrials.gov