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The Role of Budesonide Intrapolyp Injection in CRSwNP

NCT05474924 · Status: UNKNOWN · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 90

Last updated 2022-07-26

No results posted yet for this study

Summary

Chronic rhinosinusitis with nasal polyps is a common nasal comorbidity with a wide range of symptoms that might cause severe distress and disabilities for patients. Many patients undergo repeated courses of systemic steroids and are exposed to various adverse effects. many cases finally revert to surgery. Budesonide was safely used as a nasal wash in cases of nasal polyps, our aim to determine If intrapolyp injection is a better method for delivering budesonide.

Conditions

  • CRS
  • Polyp, Nasal

Interventions

DRUG

Budesonide intrapolyp injection

intrapolyp injection of budesonide in cases of nasal polyps and assessment of side effects compared to systemic steroids

DRUG

Budesonide nasal wash

Budesonide Nasal wash in cases of nasal polyp 0.5 mg/2ml added to 250 ml normal saline using squeeze bottle.

DRUG

Prednisolone tablets

oral prednisolone tablet dosage 1 mg/kg/d tapered daily for 2 weeks.

Sponsors & Collaborators

  • Kafrelsheikh University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-08-01
Primary Completion
2022-09-01
Completion
2022-12-01

Countries

  • Egypt

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05474924 on ClinicalTrials.gov