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Effects of Vitamin C Enriched Hydrolyzed Collagen, PrimaColl™, Whey Protein, or Placebo on Collagen Synthesis

NCT05427279 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20

Last updated 2026-05-08

No results posted yet for this study

Summary

The purpose of this study is to determine the effects of repeated dosing vitamin C enriched hydrolyzed collagen (HC) over a 24hr period, compared to PrimaColl™ (PC), whey protein (WP) and placebo (PL), with prescribed exercise on collagen synthesis.

To achieve this, participants will consume a supplemental dose of HC (20g with 50mg vitamin C), PC (20g with 50mg vitamin C), whey protein (20g whey isolate with 50mg vitamin C) or a placebo (20g maltodextrin with 50mg vitamin C) 1hr prior to an exercise bout (6 minutes of jump rope), this will be repeated three times over a 24h period.

The amount of collagen protein synthesized will be indirectly measured by measuring pro-collagen type I N-terminal propeptide (PINP) in the serum before and 4hrs after the last exercise bout.

Conditions

  • Effect of Food Supplement

Interventions

DIETARY_SUPPLEMENT

Placebo

The participant will consume a supplemental dose of a placebo (20g maltodextrin with 50mg vitamin C)

DIETARY_SUPPLEMENT

Hydrolized Collagen

The participant will consume a supplemental dose of Hydrolized collagen (20g with 50mg vitamin C)

DIETARY_SUPPLEMENT

PrimaColl

The participant will consume a supplemental dose of PrimaColl, a vegan collagen supplementation (20g with 50mg vitamin C)

DIETARY_SUPPLEMENT

Whey protein

The participant will consume a supplemental dose of whey protein (20g whey isolate with 50mg vitamin C)

Sponsors & Collaborators

  • Geltor

    collaborator UNKNOWN

  • University of California, Davis

    lead OTHER

Principal Investigators

  • Keith Baar, PhD · UC Davis

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
TRIPLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
30 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2022-10-05
Primary Completion
2023-06-30
Completion
2024-09-30

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05427279 on ClinicalTrials.gov