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Single Dose IV Methadone for Post-Op Pain

NCT05425420 · Status: COMPLETED · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 22

Last updated 2025-02-10

Study results available
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Summary

Single-center, open label, single-session study to evaluate methadone pharmacokinetics and pharmacodynamic in adults.

Conditions

  • Pain, Postoperative

Interventions

DRUG

methadone hydrochloride 0.1mg/kg

Single dose of methadone hydrochloride administered via intravenous (IV)

Sponsors & Collaborators

  • Kanecia Obie Zimmerman

    lead OTHER

Principal Investigators

  • Kanecia Zimmerman, MD, MPH,PhD · DUMC, DCRI

Study Design

Allocation
NA
Purpose
OTHER
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-08-11
Primary Completion
2024-01-20
Completion
2024-01-20
FDA Drug
Yes

Countries

  • United States

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05425420 on ClinicalTrials.gov