Methadone, Morphine, or Oxycodone in Treating Pain in Patients With Cancer
NCT00726830 · Status: TERMINATED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 1
Last updated 2020-09-24
Summary
RATIONALE: Methadone, morphine, or oxycodone may help relieve pain caused by cancer. It is not yet known whether methadone is more effective than morphine or oxycodone in treating pain in patients with cancer.
PURPOSE: This randomized clinical trial is studying methadone to see how well it works compared with morphine or oxycodone in treating pain in patients with cancer.
Conditions
- Brain and Central Nervous System Tumors
- Chronic Myeloproliferative Disorders
- Leukemia
- Lymphoma
- Lymphoproliferative Disorder
- Multiple Myeloma and Plasma Cell Neoplasm
- Myelodysplastic Syndromes
- Myelodysplastic/Myeloproliferative Neoplasms
- Pain
- Precancerous Condition
- Unspecified Adult Solid Tumor, Protocol Specific
Interventions
- DRUG
-
methadone hydrochloride
Given orally
- DRUG
-
morphine sulfate
Given orally
- DRUG
-
oxycodone hydrochloride
Given orally
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
M.D. Anderson Cancer Center
lead OTHER
Principal Investigators
-
Michael J. Fisch, MD, MPH, FACP · M.D. Anderson Cancer Center
-
James D. Bearden, MD · CCOP - Upstate Carolina
Study Design
- Allocation
- RANDOMIZED
- Purpose
- SUPPORTIVE_CARE
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2009-03-31
- Primary Completion
- 2010-09-30
- Completion
- 2010-10-31
Countries
- United States
Study Locations
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