Switching From Morphine to Methadone. A Clinical, Pharmacological and Pharmacogenetic Study
NCT00184496 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 42
Last updated 2014-02-28
Summary
Cancer patients on morphine for chronic pain, with side effects or unsatisfactory pain relief, will be rotated to Methadone. We will try to find out what is the best methode to rotate, and the equivalent dosage.
Conditions
Interventions
- DRUG
-
Methadone
To methods for switching morphine to methadon. Stop-and go versus overlap
Sponsors & Collaborators
-
Norwegian University of Science and Technology
lead OTHER
Principal Investigators
-
Stein Kaasa, MD,PhD Prof. · St Olavs University Hospital, Trondheim
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2004-08-31
- Primary Completion
- 2009-09-30
- Completion
- 2009-09-30
Countries
- Norway
Study Locations
More Related Trials
-
Treatment of Pain in Head-and-Neck Cancer Patients: is Methadone More Effective?
NCT01317589 ·Status: COMPLETED ·Phase: PHASE4
-
Efficacy and Safety of Ultra-low Dose Methadone as Adjuvant Analgesic in Cancer Patients With Pain
NCT02687347 ·Status: UNKNOWN ·Phase: PHASE3
-
Methadone Associated With Morphine for Cancer Pain
NCT03324815 ·Status: UNKNOWN ·Phase: NA
-
Comparison of A Single Dose Combination of Methadone and Morphine With Morphine Alone for Treating Post-operative Pain
NCT00142519 ·Status: COMPLETED ·Phase: PHASE2
-
Prospective Study About Clinical and Pharmacogenetic Safety of Opioid Use for Chronic Pain
NCT00916890 ·Status: SUSPENDED ·Phase: PHASE4
-
Nasal Fentanyl for Patient Controlled Treatment of Pain in Cancer
NCT01248611 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Methadone Versus Morphine for Cancer-Related Pain
NCT00573937 ·Status: TERMINATED ·Phase: PHASE2
-
Methadone, Morphine, or Oxycodone in Treating Pain in Patients With Cancer
NCT00726830 ·Status: TERMINATED ·Phase: NA
-
Role of Methadone As Co-Opioid Analgesic
NCT00558870 ·Status: TERMINATED ·Phase: PHASE2
-
Efficacy and Safety of Fentanyl ETHYPHARM for Breakthrough Pain in Opioid-treated Patients With Cancer
NCT01842893 ·Status: COMPLETED ·Phase: PHASE3
-
Opioid Misuse in Patients with Cancer
NCT06489769 ·Status: RECRUITING
-
Individualized Pharmaceutical-care in Outpatients With Cancer Pain
NCT03439904 ·Status: UNKNOWN ·Phase: NA
-
Sublingual Methadone for the Management of Cancer-related Procedure Pain in Inpatients
NCT00351637 ·Status: TERMINATED ·Phase: PHASE2
-
Opioid Rotation Versus Combination for Chronic Uncontrolled Cancer Pain
NCT00478101 ·Status: COMPLETED ·Phase: PHASE2
-
Study of Breakthrough Cancer Pain: Assessment of Fentanyl Buccal Tablets Titration and Treatment in Opioid-Tolerant Patients
NCT00842829 ·Status: TERMINATED ·Phase: PHASE4
-
Usefulness of Acetaminophen Associated With Strong Opioids for Acute Pain in Cancer Patients
NCT04779567 ·Status: COMPLETED ·Phase: PHASE4
-
Individualized Pharmaceutical-care for Inpatients With Cancer Pain
NCT03455023 ·Status: UNKNOWN ·Phase: NA
-
A Safety and Efficacy Study of Sufentanil Transdermal System in Patients With Chronic Pain Due to Cancer
NCT00943566 ·Status: WITHDRAWN ·Phase: PHASE2
-
Study of Opioid Rotation Versus Opioid Escalation in Patients With Moderate to Severe Cancer Pain
NCT02084355 ·Status: UNKNOWN ·Phase: PHASE3
-
Levorphanol as a Second Line Opioid in Reducing Pain in Patients With Cancer
NCT03579446 ·Status: TERMINATED ·Phase: EARLY_PHASE1
-
Fentanyl Matrix Application for Cancer Pain: Multicenter, Prospective, Observational Study
NCT01816503 ·Status: COMPLETED
-
Investigation of Analgesic and Anti-hyperalgesic Effect of Opioids in Experimental Pain
NCT00647127 ·Status: COMPLETED ·Phase: PHASE3
-
Correlation Between the Analgesic Effect of Fentanyl Transdermal Patches and Nutritional Status in Cancer Pain Patients
NCT06369961 ·Status: COMPLETED
-
Paracetamol for Cancer Pain
NCT01313247 ·Status: UNKNOWN ·Phase: PHASE4
-
Effect of Good Pain Management (GPM) Ward Program on Moderate to Severe Cancer Pain Patients
NCT03155516 ·Status: UNKNOWN ·Phase: NA