Treatment of Cabotamig (ARB202) in Advanced Gastrointestinal Cancer Patients
NCT05411133 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 33
Last updated 2026-03-19
Summary
This study aims to find out:
1. The tolerability of Cabotamig (ARB202) in adults with advanced solid gastrointestinal tumors who failed the standard treatment. People can participate if their tumor has the CDH17 marker.
2. To find out how study drug is broken down in the body
3. To know the effects of the study drug on the tumor.
Conditions
- Gastrointestinal Cancer
- Cholangiocarcinoma
- Liver Cancer
- Colorectal Adenocarcinoma
- Pancreatic Cancer
- Gastric Cancer
- Esophageal Adenocarcinoma
- Gastroesophageal Junction
- Gastrointestinal Neuroendocrine Tumors
Interventions
- DRUG
-
Cabotamig (ARB202)
Cabotamig (ARB202), Atezolizumab
Sponsors & Collaborators
-
Arbele Pty Ltd
lead INDUSTRY
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SEQUENTIAL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-05-30
- Primary Completion
- 2025-07-23
- Completion
- 2025-07-23
- FDA Drug
- Yes
Countries
- Australia
- Hong Kong
Study Locations
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