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Pro-vascular Regenerative Cell Exhaustion in Women With Polycystic Ovarian Syndrome

NCT05410834 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 30

Last updated 2022-06-08

No results posted yet for this study

Summary

PCOS-RCE is an observational, cross-sectional, two-arm study that is aimed at determining if an established diagnosis of polycystic ovarian syndrome (PCOS) influences the number of blood vessel-forming stem cells in the bloodstream. Circulating progenitor cells will be enumerated and the distribution patterns of these cell types will be assessed to determine if these parameters differ between individuals with PCOS and individuals without PCOS. Specifically, this study will evaluate if differential regenerative cell exhaustion (RCE) may account, at least in part, for the differences in cardiovascular risk reported between individuals with a diagnosis of PCOS and those without.

Conditions

  • Polycystic Ovary Syndrome

Sponsors & Collaborators

  • Canadian Medical and Surgical Knowledge Translation Research Group

    lead OTHER

Principal Investigators

  • Subodh Verma, MD, PhD · University of Toronto

  • David A Hess, PhD · University of Western Ontario, Canada

Eligibility

Min Age
30 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2022-06-30
Primary Completion
2023-02-28
Completion
2023-04-30

Countries

  • Canada

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05410834 on ClinicalTrials.gov