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Pro- and Anti-inflammatory Cytokines in PCOS

NCT06793085 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 100

Last updated 2026-03-18

No results posted yet for this study

Summary

The study will involve measurements and comparisons of the concentrations of pro-inflammatory cytokines: IL-6, TNF-α, IL-18, as well as anti-inflammatory cytokine IL-4 in women with polycystic ovary syndrome (PCOS) and insulin resistance, women with polycystic ovary syndrome without carbohydrate metabolism disorders, and women without PCOS (control group).

Conditions

  • Reproductive Age
  • PCOS (Polycystic Ovary Syndrome)

Interventions

DIAGNOSTIC_TEST

Measurement of interleukin-6 (il-6) concentration in blood serum

Measurement of fasting interleukin-6 (il-6) concentration in fasting venous blood serum

DIAGNOSTIC_TEST

Measurement of fasting tumor necrosis factor α (TNF-α) concentration

Measurement of fasting tumor necrosis factor α concentration in fasting venous blood serum

DIAGNOSTIC_TEST

Measurement of interleukin-18 (il-18) concentration

Measurement of interleukin-18 (il-18) concentration in fasting venous blood serum

DIAGNOSTIC_TEST

Measurement of interleukin-4 (il-4) concentration

Measurement of interleukin-4 (il-4) concentration in fasting venous blood plasma

Sponsors & Collaborators

  • Jagiellonian University

    lead OTHER

Principal Investigators

  • Kazimierz Pityński, Prof., Ph.D., M.D. · Jagiellonian University

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-01-20
Primary Completion
2026-06-30
Completion
2026-12-31

Countries

  • Poland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06793085 on ClinicalTrials.gov