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Comparison of the Breast Tumor Microenvironment

NCT03165487 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 14

Last updated 2025-08-22

No results posted yet for this study

Summary

The goal of the project is to identify a molecular signature of tumor stroma from "normal" adjacent breast tissue obtained prospectively at the time of breast conserving surgery before and after receiving intraoperative radiation therapy (IORT) in subjects that have luminal A and triple negative breast cancer. IORT is considered as being standard of care.

Conditions

Interventions

OTHER

Breast tissue collection

During Breast Conservation Surgery, one sample will be collected before and after IORT.

OTHER

Blood sample collection

Blood will be collected before and after IORT, and at the two week follow-up.

Sponsors & Collaborators

Principal Investigators

  • Eileen Connolly, MD · Assistant Professor of Radiation Oncology

Eligibility

Min Age
50 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-09-28
Primary Completion
2027-12-01
Completion
2027-12-01

Countries

  • United States

Study Locations

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Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03165487 on ClinicalTrials.gov