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Backward Masking Tasks to Decipher Impaired Input-Output Connections in MS @7T

NCT05377671 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 40

Last updated 2022-10-19

No results posted yet for this study

Summary

Multiple sclerosis (MS) is a chronic inflammatory and neurodegenerative disease of the central nervous system. People with MS frequently suffer from cognitive and visual impairment. Moreover, patients rank cognition and vision as two of the three most valuable bodily functions, in addition to mobility. Here the investigator use the established backward masking paradigm to study structural and functional alteration at the sub-milimeter scale in ultra-high field MRI in order to decipher the different input-output loops associated with the preservation and alteration of cognition in MS.

Conditions

  • Difference in Regional Brain Activity

Interventions

DIAGNOSTIC_TEST

IRM multimodale a ultra-haute camp

The MRI includes, in addition to structural task sequences, diffusion imaging and resting state fMRI.

Sponsors & Collaborators

  • Assistance Publique Hopitaux De Marseille

    lead OTHER

Principal Investigators

  • François CREMIEUX · ASSISTANCE PUBLIQUE HOPITAUX MARSEILLE

  • Jan-Patrick STELLMANN · ASSISTANCE PUBLIQUE HOPITAUX MARSEILLE

Study Design

Allocation
NON_RANDOMIZED
Purpose
DIAGNOSTIC
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2022-10-13
Primary Completion
2023-10-31
Completion
2024-01-31

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05377671 on ClinicalTrials.gov