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Early Cognitive Impairment in Multiple Sclerosis

NCT01157728 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 69

Last updated 2012-07-31

No results posted yet for this study

Summary

Cognitive impairment is one of the symptoms of Multiple Sclerosis (MS), and it may occur during the first years of the disease. It usually affects attention, information processing speed and short term memory. To date, the mechanisms of this specific symptom remain unclear (local or global inflammation, neurodegenerative processes).

Magnetic Resonance Imaging (MRI) can be useful to understand the pathophysiology of cognitive impairment in MS. The investigators will combine conventional and non conventional MRI sequences to determine the respective role of white matter and grey matter injury and the cortical reorganization of neuronal networks.

Conditions

Sponsors & Collaborators

  • ARSEP (Association pour la Recherche sur la Sclerose en Plaques)

    collaborator UNKNOWN

  • JNLF (Journées de Neurologie de Langue Française)

    collaborator UNKNOWN

  • Assistance Publique - Hôpitaux de Paris

    lead OTHER

Principal Investigators

  • Bruno Stankoff, MD,PhD · Pitié-Salpêtrière Hospital

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2008-05-31
Primary Completion
2010-12-31
Completion
2010-12-31

Countries

  • France

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01157728 on ClinicalTrials.gov