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Involvement of the Mediodorsal Nucleus of the Thalamus in Higher Order Cognitive Processes

NCT03867149 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 40

Last updated 2020-01-14

No results posted yet for this study

Summary

The aim is to expand evidence about the importance of the mediodorsal nucleus of the thalamus as a key node in human higher-order cognitive functions such as learning, decision-making, and adaptive behavior. Thus, the project proposes to assess global cognition along with higher-order cognition integrity via sensitive behavior tasks in patients with well localized lesions (mediodorsal thalamic infarcts) compared with healthy participants.

Conditions

  • Thalamic Infarction

Interventions

OTHER

neuroimaging

neuroimaging including high-resolution imaging of the thalamus, DTI and resting state fMRI

OTHER

Neuropsychological assessment

neuropsychological assessment of memory, language, executive functions and mood

Sponsors & Collaborators

  • Institut National de la Santé Et de la Recherche Médicale, France

    collaborator OTHER_GOV

  • University Hospital, Toulouse

    lead OTHER

Principal Investigators

  • Jérémie PARIENTE, MD, PHD · University Hospital, Toulouse

Study Design

Allocation
NON_RANDOMIZED
Purpose
DIAGNOSTIC
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-05-14
Primary Completion
2023-04-30
Completion
2023-04-30

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03867149 on ClinicalTrials.gov