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Adaptive Optics Imaging of Outer Retinal Diseases

NCT05355415 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 100

Last updated 2026-05-08

No results posted yet for this study

Summary

The objective of the study is to collect adaptive optics (AO) retinal images from human subjects with outer retinal diseases (diseases of the outer retina including photoreceptor, retinal pigment epithelium (RPE), basement membrane or choroidal pathologies) to develop new diagnostic methods, biomarkers, and clinical endpoints.

Conditions

  • Retinal Degeneration
  • Age-Related Macular Degeneration
  • Retinitis Pigmentosa
  • Hydroxychloroquine Retinopathy
  • Usher Syndromes
  • Late-Onset Retinal Degeneration
  • Cone Dystrophy
  • Cone Rod Dystrophy
  • Rod Cone Dystrophy
  • Rod Dystrophy

Interventions

DEVICE

Adaptive optics imaging

Adaptive optics scanning laser ophthalmoscopy (AOSLO) and adaptive optics - optical coherence tomography (AO-OCT) retinal imaging

Sponsors & Collaborators

  • National Eye Institute (NEI)

    collaborator NIH

  • Food and Drug Administration (FDA)

    lead FED

Principal Investigators

  • Daniel X Hammer, Ph.D. · Food and Drug Administration (FDA)

Eligibility

Min Age
21 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-08-27
Primary Completion
2028-09-30
Completion
2028-09-30
FDA Device
Yes

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05355415 on ClinicalTrials.gov