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Adaptive Optics Retinal Imaging

NCT02317328 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 1000

Last updated 2026-05-11

No results posted yet for this study

Summary

Background:

\- By the time diseases of the retina are detected, serious damage has often already been done. Researchers want to find better ways of viewing the retina. One way called adaptive optics may help detect problems earlier.

Objectives:

\- To study if adaptive optics can help find better ways to diagnose, treat, and manage retinal diseases.

Eligibility:

* People over age 12 with an eye disease.
* Healthy volunteers over age 12.

Design:

* Participants will be screened with medical history and eye exams. These may include dilating pupils and taking pictures of the eyes.
* Participants will have 1 or more study visits. They will have:
* Medical and eye history.
* Questions about their medications.
* Eye exam including pupil dilation.
* Adaptive optics imaging. After dilation, participants sit still while looking into an adaptive optics instrument. They look at specific places and images are taken of their retina.
* They may also have:
* More images.
* Perimetry. Participants look into a lens and press a button when they see a light.
* Color vision tests.
* Electroretinogram. Participants will get numbing eye drops and special contact lenses. A small metal electrode will be put on their forehead. They will look at flashing lights and try not to blink.

Conditions

  • Eye Diseases
  • Healthy Volunteers

Sponsors & Collaborators

  • National Eye Institute (NEI)

    lead NIH

Principal Investigators

  • Johnny C Tam, Ph.D. · National Eye Institute (NEI)

Eligibility

Min Age
12 Years
Max Age
120 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2015-02-20
Primary Completion
2028-03-31
Completion
2028-03-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02317328 on ClinicalTrials.gov