MedTrace Logo

Optimizing Cerebral Autoregulation During Surgery

NCT05308290 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 27

Last updated 2025-09-02

Study results available
· View outcomes & findings →

Summary

The purpose of this study is to conduct a pilot trial to determine the feasibility, safety, and potential efficacy of targeting mean arterial blood pressure (MAP) within the limits of cerebral autoregulation during surgery compared with usual care.

Conditions

  • Hip Fractures
  • Hip Arthropathy
  • Surgery
  • Delirium

Interventions

OTHER

Blood pressure management according to cerebral autoregulation

Intraoperative blood pressure will be targeted based on limits of cerebral autoregulation.

OTHER

Blood pressure management according to usual care

Intraoperative blood pressure will be targeted based on usual care.

Sponsors & Collaborators

Principal Investigators

  • Charles Brown, MD · Johns Hopkins University

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
60 Years
Max Age
100 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-01-09
Primary Completion
2024-06-28
Completion
2025-07-30

Countries

  • United States

Study Locations

More Related Trials

Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05308290 on ClinicalTrials.gov