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Precision Medicine Approach to Unravel the Risk Factors for Renal, Cardiovascular, Ophthalmologic, Neurologic and Hepatic Complications of Metabolic Disorders

NCT05307172 · Status: WITHDRAWN · Type: OBSERVATIONAL

Last updated 2025-05-16

No results posted yet for this study

Summary

There is currently no way to predict the progression of chronic kidney disease in patients with metabolic disease(s). Furthermore, the mechanisms responsible for the development and/or progression of complications remain largely unknown.

In order to identify the predictive factors and/or mechanisms involved in the different complications of these diseases, we propose an approach coupling :

* a classical phenotypic characterization (clinical, biological, imaging) of the patients
* high-throughput screening of the genome, transcriptome, metabolome, proteome, and immunophenotyping.

According to our hypothesis, this approach should allow :

* Early detection of complications
* Classification of patients in homogeneous groups of patients with identical evolution
* Identification of the molecular mechanisms involved.

Conditions

Sponsors & Collaborators

  • Centre Hospitalier Universitaire, Amiens

    collaborator OTHER

  • Biobanque de Picardie

    collaborator UNKNOWN

  • Institut National de la Santé Et de la Recherche Médicale, France

    lead OTHER_GOV

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-05-03
Primary Completion
2032-05-03
Completion
2032-05-03

Countries

  • France

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05307172 on ClinicalTrials.gov