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Rt-fMRI Neurofeedback and AH in Schizophrenia

NCT03504579 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 25

Last updated 2022-11-29

No results posted yet for this study

Summary

Auditory hallucinations in schizophrenia are one of the major symptoms of this disease and a major source of psychological discomfort. They are often difficult or impossible to treat with existing methods. This study will test the use of real-time fMRI neurofeedback to mitigate auditory verbal hallucinations in patients whose hallucinations are resistant to medication. Half of the patients will receive real time fMRI neurofeedback from a brain region involved in auditory hallucinations and half will receive it from motor cortex.

Conditions

  • Audio Visual Hallucinations
  • Neurofeedback
  • Schizophrenia
  • Superior Temporal Gyrus

Interventions

OTHER

rt-fMRI neurofeedback

use of real time fMRI neurofeedback to achieve targeted brain changes

Sponsors & Collaborators

  • Harvard Medical School (HMS and HSDM)

    lead OTHER

Principal Investigators

  • margaret niznikiewicz, ph.d · VA Boston Healthcare System

  • susan whitfield-Gabrieli, Ph.D. · Massachusetts Institute of Technology

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
55 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-03-01
Primary Completion
2022-03-30
Completion
2022-06-30

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03504579 on ClinicalTrials.gov