Brain Functions Underlying Visuospatial Attention Deficits in Schizophrenia

NCT01399437 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 64

Last updated 2018-04-05

No results posted yet for this study

Summary

Background:

\- A special brain circuit is important for helping us keeping an eye open for things that are going on around us, even when we are not directly paying attention to them. This circuit seems to work differently in people with schizophrenia than in other people, which may explain specific deficits with broad monitoring observed in people with schizophrenia. Researchers want to compare brain function in people with schizophrenia and healthy volunteers to find out more about how these brain circuits work and affect attention.

Objectives:

\- To study how the brain performs broad visual monitoring in people with schizophrenia.

Eligibility:

* Individuals between 18 to 55 years of age who have been diagnosed with schizophrenia.
* Healthy volunteers between 18 and 55.

Design:

* Participants will be screened with physical and psychological exams. They will have a medical history. Tests for drug and alcohol use will also be done.
* Participants will have two study visits. The first is a training visit and the second is a scanning visit.
* At the training visit, participants will practice computer-based tests of focus, memory, and concentration. They will also answer questions about mood, psychiatric symptoms, and smoking habits.
* At the scanning visit, participants will perform the computer-based tasks that they practiced at the training visit. They will have magnetic resonance imaging while they perform these tasks.

Conditions

Sponsors & Collaborators

  • National Institute on Drug Abuse (NIDA)

    lead NIH

Principal Investigators

  • Elliot Stein, Ph.D. · National Institute on Drug Abuse (NIDA)

Eligibility

Min Age
18 Years
Max Age
55 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2011-07-03
Completion
2014-12-24

Countries

  • United States

Study Locations

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Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01399437 on ClinicalTrials.gov