STUDY INCIDENCE AND CHARACTERISTICS OF MALIGNANT NEOPLASIES IN PATIENTS WITH HEMOGLOBINOPATHY FOLLOWED IN ITALY
NCT05286138 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 10000
Last updated 2022-04-01
Summary
The Trial aims to increase the information available on the relevance of tumor pathology in hemoglobinopathies, updating the data relating to hepatocarcinoma and investigating which other tumors are more frequent in patients with hemoglobinopathies. Still, in relation to tumor pathology, the study will evaluate any differences between the different types of hemoglobinopathy and will investigate the association between the appearance of neoplasms and risk factors such as age, sex, iron accumulation markers, history of bone marrow transplant, and others.
Conditions
- Malignacy, Hemoglobinopathie
Sponsors & Collaborators
-
Società Italiana Talassemie ed Emoglobinopatie
lead OTHER
Principal Investigators
-
RAFFAELLA ORIGA, MD · Azienda Ospedaliero Universitaria di Cagliari
Eligibility
- Min Age
- 18 Years
- Max Age
- 100 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-02-01
- Primary Completion
- 2024-02-28
- Completion
- 2052-02-28
Countries
- Italy
Study Locations
More Related Trials
-
Monitoring of Anti-SARS-CoV-2 (COVID 19) and Encapsulated Vaccination Patients With Thalassemic and Falcemic Syndromes
NCT05157256 ·Status: ACTIVE_NOT_RECRUITING
-
GenoMed4ALL: Improving SCD Classification and Prognosis by AI
NCT06019208 ·Status: UNKNOWN
-
Biological, Genetic and Environmental Involved in the Complications of Sickle Cell Disease
NCT04205123 ·Status: UNKNOWN
-
Atrial Fibrillation in Beta-Thalassemia
NCT05508932 ·Status: RECRUITING
-
Transfusion Treatment in Patients With SCD
NCT03397017 ·Status: COMPLETED
-
Total Splenectomy vs Partial Splenectomy in Non-malignant Hemoglobinopathies : Study Comparing the Effectiveness
NCT05184647 ·Status: UNKNOWN
-
Sickle Cell Anemia - A Comparative Study Between Three Ethnical Communities, a Multicenter Study
NCT01905787 ·Status: UNKNOWN
-
Avascular Bone Necrosis in Sickle Cell Disease: a Pediatric Study.
NCT05203991 ·Status: COMPLETED
-
Vitamin D and Bisphosphonates in the Treatment of Sickle Cell Disease
NCT02972138 ·Status: COMPLETED
-
Clinical Management of Hereditary Hemochromatosis: Phlebotomy vs. Erythrocytoapheresis
NCT00440986 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Transfusion in Sickle Cell Disease: Risk Factors for Alloimmunization
NCT03405402 ·Status: COMPLETED ·Phase: NA
-
Bone Status on Patients With Genetic Hemochromatosis: a 3 Years Descriptive and Evolutionary Study
NCT01556360 ·Status: COMPLETED
-
Pathophysiology of Acute Pain in Patients With Sickle Cell Disease
NCT03049475 ·Status: COMPLETED
-
Identification of Factors Associated With Treatment Response in Patients With Polycythemia Vera, Essential Thrombocythemia, and Pre-myelofibrosis.
NCT05440838 ·Status: RECRUITING
-
Functional and Mechanistic Characterization of Limb Ulcers in Patients With Sickle Cell Disease
NCT04983654 ·Status: COMPLETED ·Phase: NA
-
Rare Iron Overloads Except C282Y Homozygosity : Description and Characterization.
NCT01541813 ·Status: TERMINATED
-
Oxidative Stress and Iron Overload in Patient With Abnormal Haemoglobinopathy
NCT05586932 ·Status: UNKNOWN
-
A Study to Access the Safety/Efficacy of Thalidomide in the Treatment of Anemia in Patients With Myelodysplastic Syndromes
NCT00050843 ·Status: COMPLETED ·Phase: PHASE3
-
Study of Individuals Affected With Hypoplasminogenemia
NCT03797495 ·Status: RECRUITING
-
Monitoring of Erythroid Lineage Specific Chimerism Following Allogeneic Hematopoietic Transplantation for Thalassemia Major
NCT00480506 ·Status: COMPLETED
-
Study to Evaluate Efficacy and Safety of S303 Treated Red Blood Cells (RBCs)in Subjects With Thalassemia Major Requiring Chronic RBC Transfusion
NCT01740531 ·Status: COMPLETED ·Phase: PHASE3
-
Identification of Mechanism in the Erythroid Response in Patients With Myelodysplasia Undergoing Chelation Therapy
NCT01956799 ·Status: COMPLETED
-
The Influence of micro-and Macro Vascular Dysfunction on Clinical Severity in Adults With Sickle Cell Anemia (SS) and Sickle Cell Hemoglobin C Disease (SC)
NCT07277023 ·Status: COMPLETED ·Phase: NA
-
Survey in a Population of Sickle Cell Disease Patients to Evaluate the Transition Between the Queen Fabiola Children Hospital and the CHU Brugmann Hospital, and the Quality of the Hospital Care Within the CHU Brugmann Hospital.
NCT02608580 ·Status: COMPLETED ·Phase: NA
-
A Study of Darbepoetin Alfa in Anemic Subjects With Low Risk Myelodysplastic Syndrome
NCT00095264 ·Status: COMPLETED ·Phase: PHASE2