A Study to Access the Safety/Efficacy of Thalidomide in the Treatment of Anemia in Patients With Myelodysplastic Syndromes

A Study to Determine the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of AG-348 in Adult Participants With Non-transfusion-dependent Thalassemia

NCT03692052 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2

A Study of Nicotinamide With Oral Tetrahydrouridine and Decitabine to Treat High Risk Sickle Cell Disease

NCT04055818 ·Status: RECRUITING ·Phase: PHASE1

Phase I/II Randomized Study of Hydroxyurea With or Without Clotrimazole in Patients With Sickle Cell Anemia

NCT00004492 ·Status: COMPLETED ·Phase: PHASE1/PHASE2

Evaluating the Safety and Effectiveness of Decitabine in People With Thalassemia Intermedia

NCT00661726 ·Status: COMPLETED ·Phase: PHASE2

A Dose-Finding Study of AG-348 in Sickle Cell Disease

NCT04000165 ·Status: COMPLETED ·Phase: EARLY_PHASE1

Haploidentical Hematopoietic Stem Cell Transplantation

NCT02165007 ·Status: COMPLETED ·Phase: PHASE1

A Study to Evaluate Safety, Pharmacokinetic, and Biological Activity of INCB059872 in Subjects With Sickle Cell Disease

NCT03132324 ·Status: TERMINATED ·Phase: PHASE1

A Study to Evaluate GBT021601-012 Single Dose and Multiple Dose in Participants With Sickle Cell Disease (SCD)

NCT04983264 ·Status: COMPLETED ·Phase: PHASE1

CS-206 in Patients With Sickle Cell Disease

NCT07000318 ·Status: NOT_YET_RECRUITING ·Phase: EARLY_PHASE1

Gene Correction in Autologous CD34+ Hematopoietic Stem Cells (HbS to HbA) to Treat Severe Sickle Cell Disease

NCT04819841 ·Status: RECRUITING ·Phase: PHASE1/PHASE2

Hematopoietic Stem Cell Transplantation for Patients With Thalassemia Major: A Multicenter, Prospective Clinical Study

NCT04009525 ·Status: COMPLETED ·Phase: PHASE4

Pharmacokinetics, Pharmacodynamics and Safety of Epeleuton in Patients With Sickle Cell Disease

NCT05861453 ·Status: COMPLETED ·Phase: PHASE2

Dose-Escalation Study of SCD-101 in Sickle Cell Disease

NCT02380079 ·Status: UNKNOWN ·Phase: PHASE1

Clinical Experience of Thalidomide in Thalassemic Patients

NCT05132270 ·Status: COMPLETED ·Phase: PHASE2/PHASE3

Phase II Study of Arginine Butyrate With or Without Epoetin Alfa in Patients With Thalassemia Intermedia

NCT00006136 ·Status: COMPLETED ·Phase: PHASE2

Study to Determine the Maximum Tolerated Dose, Safety and Effectiveness of Pomalidomide for Patients With Sickle Cell Disease

NCT01522547 ·Status: COMPLETED ·Phase: PHASE1

5-Azacytidine and Phenylbutyrate to Treat Severe Thalassemia

NCT00005934 ·Status: COMPLETED ·Phase: PHASE2

Study of High-Dose Pulse Administration DN-101 (Calcitriol) in Patients With Myelodysplastic Syndrome (MDS)

NCT00057031 ·Status: UNKNOWN ·Phase: PHASE2

Repeat Peripheral Blood Stem Cell Transplantation for Patients With Sickle Cell Disease and Falling Donor Myeloid Chimerism Levels

NCT04008368 ·Status: RECRUITING ·Phase: PHASE1/PHASE2

A Phase I/II Study of ITU512 in Healthy Participants and Patients With Sickle Cell Disease

NCT06546670 ·Status: RECRUITING ·Phase: PHASE1/PHASE2

Study of Deferasirox in Iron Overload From Beta-thalassemia Unable to be Treated With Deferoxamine or Chronic Anemias

NCT00061763 ·Status: COMPLETED ·Phase: PHASE2

Screening for Alpha Thalassemia in Healthy Volunteers

NCT02692872 ·Status: ACTIVE_NOT_RECRUITING

Study of SDMB (2,2 Dimethylbutyrate, Sodium Salt) in Beta Thalassemia Intermedia in Thailand

NCT01609595 ·Status: COMPLETED ·Phase: PHASE2

This Study Will Evaluate Efficacy and Safety of Deferasirox in Patients With Myelodysplastic Syndromes (MDS), Thalassemia and Rare Anemia Types Having Transfusion-induced Iron Overload.

NCT01250951 ·Status: COMPLETED ·Phase: PHASE4

A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AG-946 in Healthy Volunteers and in Participants With Sickle Cell Disease

NCT04536792 ·Status: COMPLETED ·Phase: PHASE1