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Red Blood Cell - IMProving trAnsfusions for Chronically Transfused Recipients

NCT05255445 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 157

Last updated 2024-05-17

No results posted yet for this study

Summary

Red Blood Cell - IMProving trAnsfusions for Chronically Transfused recipients (RBC-IMPACT) is an observational cohort study to assess donor, component, and recipient factors that contribute to RBC efficacy in chronically and episodically transfused patients. The objective of the study is to determine how specific genetic and non-genetic factors in donors and recipients may impact RBC survival after transfusion - in short, what factors on both the donor and recipient side may improve the efficacy of the transfusion.

Conditions

Interventions

BIOLOGICAL

Red Blood Cell (RBC) Transfusion

Simple RBC transfusion or partial manual exchange

Sponsors & Collaborators

  • National Heart, Lung, and Blood Institute (NHLBI)

    collaborator NIH

  • Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

    collaborator NIH

  • Westat

    lead OTHER

Principal Investigators

  • Eldad A Hod, MD · Columbia University

  • Brian Custer, PhD, MPH · Vitalant Research Institute

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-03-16
Primary Completion
2024-03-31
Completion
2024-03-31
FDA Drug
Yes

Countries

  • United States
  • Brazil

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05255445 on ClinicalTrials.gov