MedTrace Logo

Safety and Tolerability of Nitro for Radial Artery Dilation

NCT05239013 · Status: UNKNOWN · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 20

Last updated 2022-04-06

No results posted yet for this study

Summary

Phase 1, single-center, open-label clinical study to assess the safety and efficacy of topical nitroglycerin on dilation of the radial artery. Subjects will receive nitroglycerin ointment prior to scheduled PCI and radial artery measurements will be performed to determine mean increase in radial artery diameter at several time points. There will be 20 subjects enrolled in this study.

Conditions

  • Artery; Dilatation

Interventions

DRUG

Nitroglycerin ointment

2 cm (30mg) of 2% nitroglycerin applied 2 cm from the styloid process of the anterior forearm

Sponsors & Collaborators

  • Thomas Jefferson University

    lead OTHER

Principal Investigators

  • David Fischman, M.D. · Thomas Jefferson University

Study Design

Allocation
NA
Purpose
OTHER
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2022-05-01
Primary Completion
2023-03-01
Completion
2023-03-01
FDA Drug
Yes

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05239013 on ClinicalTrials.gov