Multi-domain Online Therapeutic Investigation Of Neurocognition (MOTION)
NCT05217849 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 77
Last updated 2026-02-09
Summary
The purpose of this study is to compare the effects of three on-line wellness interventions for improving physical and cognitive function and brain connectivity in adults who are at least 55 years old and are experiencing symptoms of memory and/or cognitive difficulties.
Conditions
- Mild Cognitive Impairment
- Subjective Memory Decline
Interventions
- BEHAVIORAL
-
Tai Chi
Tai Chi is an ancient Chinese form of exercise/martial art that involves a series of movements performed in a slow, focused manner and accompanied by deep breathing.
- BEHAVIORAL
-
Preventing Loss of Independence through Exercise (PLIE)
PLIE is a gentle, mindful movement exercise program that integrates elements of Eastern and Western exercise modalities to develop mindful body awareness and enhance social connection.
- BEHAVIORAL
-
Health and Wellness Education
This on-line class will consist of hour-long lectures/talks about various topics related to healthy aging and wellness.
Sponsors & Collaborators
-
San Francisco VA Health Care System
collaborator FED -
University of California, Los Angeles
collaborator OTHER -
United States Department of Defense
collaborator FED -
CDMRP
collaborator UNKNOWN -
University of California, San Francisco
lead OTHER
Principal Investigators
-
Linda L Chao, PhD · University of California, San Francisco & SFVAHCS
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- SINGLE
- Model
- PARALLEL
Eligibility
- Min Age
- 55 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-02-15
- Primary Completion
- 2024-07-16
- Completion
- 2025-12-31
Countries
- United States
Study Locations
More Related Trials
-
Walking on Cognitive Function in Individuals With Mild Cognitive Impairment: A Pilot Project
NCT04498195 ·Status: COMPLETED ·Phase: NA
-
Brain Health Together: Development and Pilot Test
NCT06914947 ·Status: COMPLETED
-
Train Your Brain Fitness SC: An Exercise Intervention for People With Cognitive Impairments
NCT06799429 ·Status: RECRUITING ·Phase: NA
-
The Effect of Exercise on Neurorecovery Following Mild Traumatic Brain Injury
NCT02276079 ·Status: COMPLETED ·Phase: NA
-
Sensory-cognitive and Physical Fitness Training in Mild Cognitive Impairment
NCT01061489 ·Status: COMPLETED ·Phase: NA
-
A Pilot Study for Efficacy of Cognitive and Physical Training in Patients With Mild Cognitive Impairment
NCT06355973 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Cognitive and Aerobic Resilience for the Brain
NCT02390453 ·Status: COMPLETED ·Phase: NA
-
Online Meditation for Mild Cognitive Impairment and Mild Dementia
NCT06768450 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
An Intergenerational, Cognitively Enriched Intervention for MCI Patients and Their Children.
NCT06221579 ·Status: ENROLLING_BY_INVITATION ·Phase: NA
-
Effects of Aerobic Exercise on Cognition,cerebral Brain Flow and Mental Health Among Traumatic Brain Injury Patients
NCT04243226 ·Status: RECRUITING ·Phase: NA
-
Functional Magnetic Resonance Imaging Study of Jaw-tapping Movement on Memory Function
NCT01873664 ·Status: UNKNOWN ·Phase: NA
-
Effects of Physical and Cognitive Training in Neuroplasticity, Health and Cognition. Movement Project
NCT03123900 ·Status: COMPLETED ·Phase: NA
-
The Effects of Mixed Working Memory Training on Subsequent Training Gains Among Older Adults
NCT05672771 ·Status: COMPLETED ·Phase: NA
-
Efficacy of Cognitive Training in Subjective Memory Impairment
NCT02555774 ·Status: COMPLETED ·Phase: NA
-
Effect of Exercise Training on Physical, Cognitive, and Behavioral Function in People With TBI
NCT02504866 ·Status: TERMINATED ·Phase: NA
-
Cognition and Neuroplasticity Sedentary Adults After 8 Weeks of Aerobic Exercise
NCT03804528 ·Status: TERMINATED ·Phase: NA
-
Physical Training and Cognitive Activity on the Mild Cognitive Impairment (MCI) Patient
NCT01553929 ·Status: TERMINATED ·Phase: NA
-
The Effect of Exercise on Mood After Traumatic Brain Injury
NCT00571545 ·Status: COMPLETED ·Phase: NA
-
Effects of Aerobic Exercise on Cognition, Mood and Fatigue Following TBI
NCT00619463 ·Status: COMPLETED ·Phase: NA
-
Cognitive Control and Physical Exercise
NCT01183819 ·Status: TERMINATED ·Phase: NA
-
Movement Intervention for Memory Enhancement
NCT03475316 ·Status: COMPLETED ·Phase: NA
-
Working Memory and Physical Exercise Training in Patients With Mild Cognitive Impairment
NCT05948930 ·Status: RECRUITING ·Phase: NA
-
Impact of Combined Behavioral Interventions on Cognitive Outcomes in MCI
NCT02864069 ·Status: COMPLETED ·Phase: NA
-
Improvisational Movement for People With Memory Loss and Their Caregivers
NCT03333837 ·Status: COMPLETED ·Phase: NA
-
Locomotion Adaptation Deficits in Older Adults With Mild Cognitive Impairment and Alzheimers Disease
NCT06484244 ·Status: RECRUITING ·Phase: NA