Role of the Oral Microbiome & Mucosal Immunity in COVID-19 Disease
NCT05212766 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 750
Last updated 2023-10-10
Summary
Determining whether in the mouth there are differences between the participant groups in the nature and activity of mucosal innate immunity, in immune responses to SARS-COV2 antigens, or in the oral microbiome
Conditions
- COVID-19
- Microbial Colonization
- Oral Disease
- Periodontal Diseases
- Innate Inflammatory Response
- Mucosal Infection
Interventions
- BIOLOGICAL
-
COVID infection
Infections with COVID 19
- BIOLOGICAL
-
COVID vaccination
Vaccination against COVID 19
- DIAGNOSTIC_TEST
-
Oral examination
Assessment of oral and periodontal health status
Sponsors & Collaborators
-
Guy's and St Thomas' NHS Foundation Trust
collaborator OTHER -
UK Research and Innovation
collaborator OTHER - lead OTHER
Principal Investigators
-
Stephen J Challacombe, PhD · King's College London
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2022-04-07
- Primary Completion
- 2023-10-30
- Completion
- 2024-12-30
Countries
- United Kingdom
Study Locations
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