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Prospective Phenotyping for Genetic Subtypes of Early-onset Atrial Fibrillation

NCT05190679 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 155

Last updated 2026-05-06

No results posted yet for this study

Summary

This is a prospective, case-control study that seeks to learn about the role of genetics in early onset atrial fibrillation (AF) and if genetic testing can be used to improve how the investigators treat atrial fibrillation. The study will enroll 225 participants. Eligible participants will have undergone sequencing for arrhythmia and cardiomyopathy (CM) genes. Based on those results, participants will be recruited for an outpatient research visit with testing that includes cardiac MRI, rest/stress/signal-averaged ECGs, and cardiac monitoring. If an inherited arrhythmia/CM syndrome is diagnosed, guideline-directed changes to medical care will be recommended.

Conditions

Interventions

OTHER

None/Observational Studies

This is an observational study and there is no intervention.

Sponsors & Collaborators

Principal Investigators

  • M. B Shoemaker, MD · Vanderbilt University Medical Center

Eligibility

Min Age
15 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-04-27
Primary Completion
2026-03-03
Completion
2026-03-03

Countries

  • United States

Study Locations

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Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05190679 on ClinicalTrials.gov