Comparison of the Substitution Between Different Tobacco/Nicotine Products as a Function of Tobacco-user Type

Summary

This study will investigate the relative appeal (abuse liability) of novel tobacco products, how the appeal is modulated by relative price, user type, and how novel products may substitute for one another.

Conditions

• Cigarette Smoking
• Nicotine Vaping

Interventions

OTHER

All nicotine/ tobacco products at market price

Nicotine/tobacco products available in the Experimental Tobacco Marketplace at market price. Note that all participants will complete all the specified conditions.

OTHER

Nicotine vaping products at 1/2 market price

Availability of nicotine vaping products in the Experimental Tobacco Marketplace at 1/2 market price. Other nicotine/tobacco products at market price. Note that all participants will complete all the specified conditions.

OTHER

Nicotine vaping products at 2x market price

Availability of nicotine vaping products in the Experimental Tobacco Marketplace at 2x market price. Other nicotine/tobacco products at market price. Note that all participants will complete all the specified conditions.

OTHER

Heated tobacco products at 1/2 market price.

Availability of heated tobacco products in the Experimental Tobacco Marketplace at 1/2 market price. Other nicotine/tobacco products at market price. Note that all participants will complete all the specified conditions.

OTHER

Heated tobacco products at 2x market price.

Availability of heated tobacco products in the Experimental Tobacco Marketplace at 2x market price. Other nicotine/tobacco products at market price. Note that all participants will complete all the specified conditions.

OTHER

Nicotine pouch products at 1/2 market price.

Availability of heated tobacco products in the Experimental Tobacco Marketplace at 1/2 market price. Other nicotine/tobacco products at market price. Note that all participants will complete all the specified conditions.

OTHER

Nicotine pouch products at 2x market price.

Availability of heated tobacco products in the Experimental Tobacco Marketplace at 2x market price. Other nicotine/tobacco products at market price. Note that all participants will complete all the specified conditions.

Sponsors & Collaborators

• Medical University of South Carolina

  collaborator OTHER

• National Cancer Institute (NCI)

  collaborator NIH

• Virginia Polytechnic Institute and State University

  lead OTHER

Principal Investigators

• Warren K Bickel, Ph.D. · Fralin Biomedical Research Institute at VTC

Study Design

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

NONE

Model

CROSSOVER

Eligibility

Min Age

21 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2022-06-29

Primary Completion

2023-06-02

Completion

2023-06-07

Countries

• United States

Study Locations