CTNNA1 Familial Expansion Study
NCT05126290 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 100
Last updated 2026-02-05
Summary
The goal of the CAFÉ Study is to determine the cancer risks associated with germline CTNNA1 loss-of-function variants.
Conditions
- Cancer Gene Mutation
- Gastric Cancer
- Breast Cancer
Interventions
- OTHER
-
Collection of personal and family history from CAFÉ Study participants
Personal medical and genetic history, as well as relevant information about family history, will be collected from participants in the CAFÉ Study through an online data entry system
Sponsors & Collaborators
-
Abramson Cancer Center at Penn Medicine
lead OTHER
Principal Investigators
-
Bryson W Katona, MD, PhD · University of Pennsylvania
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2021-03-16
- Primary Completion
- 2028-01-01
- Completion
- 2028-01-01
Countries
- United States
Study Locations
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