Universal- Versus Guidelines-Directed Genetic Testing for Germline Pathogenic Variants Utilizing a Multi-Gene Panel for Inherited Cancers in Non-Western Society.
NCT04920513 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 3000
Last updated 2025-03-19
Summary
The investigators aim to study the pattern and frequency of pathogenic variants among ALL newly diagnosed cancer patients in a genetically distinct population.
Additionally, the investigators will study the uptake rate of "cascade family screening", frequency of pathogenic variants and barriers against testing.
Conditions
- Genetic Predisposition
Sponsors & Collaborators
-
King Hussein Cancer Center
lead OTHER
Principal Investigators
-
Hikmat Abdel-Razeq · King Hussein Cancer Center
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2021-05-01
- Primary Completion
- 2025-02-01
- Completion
- 2025-02-01
Countries
- Jordan
Study Locations
More Related Trials
-
Oncology Research Information Exchange Network in Improving Genetic Screening Rate in Patients With Cancer
NCT03348137 ·Status: WITHDRAWN
-
Ascertainment of Peripheral Blood or Saliva Samples for Genetic Epidemiology Studies of Familial Cancers
NCT00579163 ·Status: ACTIVE_NOT_RECRUITING
-
Genetic Analysis of Blood and Tissue Samples From Patients With Advanced Cancer, Moonshot Study
NCT03707574 ·Status: COMPLETED
-
Clinical Genetics Branch Eligibility Screening Survey
NCT07005297 ·Status: NOT_YET_RECRUITING
-
Molecular Genetics Studies of Cancer Patients and Their Relatives
NCT04185935 ·Status: RECRUITING
-
Genetic Analysis of Inherited Urologic Malignant Disorders: Collection of Samples
NCT00001814 ·Status: COMPLETED
-
Blood Samples From Healthy Volunteers for Genetic Studies in the East Anglia Region of the United Kingdom
NCT00757991 ·Status: UNKNOWN
-
Genetic Testing in Young Adults With Cancer Study
NCT04533555 ·Status: COMPLETED ·Phase: NA
-
Cancer Genetic Testing in Ethnic Populations
NCT04475640 ·Status: RECRUITING ·Phase: NA
-
Studying Genes in Samples From Younger Patients With Acute Lymphoblastic Leukemia
NCT01653613 ·Status: UNKNOWN
-
The Genetic Education for Men Trial: Web-Based Education vs. Standard Care
NCT02957981 ·Status: COMPLETED ·Phase: NA
-
CIRculating Cell-free nUcLeic Acids in Cancer Therapy Monitoring -01
NCT05871593 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Familial Investigations of Childhood Cancer Predisposition
NCT03050268 ·Status: RECRUITING
-
Identifying and Caring for Individuals With Inherited Cancer Syndrome
NCT04494945 ·Status: RECRUITING ·Phase: NA
-
Malignant Hyperthermia Registry and Genetic Testing
NCT02964481 ·Status: TERMINATED
-
Clinical Outcomes for Offering Genetic Testing in a Tiered Approach
NCT04902144 ·Status: COMPLETED ·Phase: NA
-
A Gene Hunting Study for Familial Papillary Thyroid Cancer
NCT02776969 ·Status: ACTIVE_NOT_RECRUITING
-
Establishing a Tumor Bank in Families With Multiple Lymphoproliferative Malignancies
NCT00131014 ·Status: RECRUITING
-
Physicians Survey on Genetic Testing
NCT00341107 ·Status: COMPLETED
-
Genetic Testing in African Americans
NCT05591131 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
A Genotype-Phenotype Urothelial Cancer Registry
NCT00902590 ·Status: ACTIVE_NOT_RECRUITING
-
Collection of Blood From Patients With Cancer, Other Tumors, or Tumor Predisposition Syndromes for Genetic Analysis
NCT01441089 ·Status: RECRUITING
-
Detection of Germline and Somatic Pathogenic Variants in Patients With de Novo Metastatic Breast Cancer
NCT05758948 ·Status: UNKNOWN
-
Evaluating Microarray Pharmacogenetic Testing in Cancer Patients
NCT06489041 ·Status: RECRUITING ·Phase: NA
-
Interest and Impact of Skin Cancer Genetic Testing
NCT02941900 ·Status: COMPLETED