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The Effect of Mechanical Ventilation on the Occurrence of Myocardial Ischemia: a Pilot Study

NCT05109715 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 14

Last updated 2022-10-21

No results posted yet for this study

Summary

The goal of the proposed pilot study is to determine which method can detect myocardial ischemia at the predefined timepoints during endo-CABG. Additionally, the investigators want to examine the influence of mechanical ventilation on the occurrence of myocardial ischemia in patients undergoing endo-CABG.

Conditions

Interventions

PROCEDURE

Continued ventilation

Ventilation is continued from going on CPB until clamping of the ascending aorta with tidal volume 3ml/kg ideal body weight, Fraction of inspired oxygen (FiO2) 50%, respiratory rate 5/min and Inspiratory:Expiratory (I/E) ratio 1/2.

PROCEDURE

Discontinued ventilation

Ventilation is discontinued after going on CPB and lungs are exposed to atmospheric pressure

Sponsors & Collaborators

  • Jessa Hospital

    lead OTHER

Principal Investigators

  • Abdullah Kaya, PhD · Jessa Hospital

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-01-24
Primary Completion
2022-04-18
Completion
2022-10-04

Countries

  • Belgium

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05109715 on ClinicalTrials.gov