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Maintaining Mechanical Ventilation During Cardiopulmonary Bypass for Cardiac Surgery

NCT03372174 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 1401

Last updated 2022-05-02

No results posted yet for this study

Summary

The main objective of this study is to measure the incidence of postoperative infections in 2 groups of patients: one group of patients ventilated and one group of patients without mechanical ventilation during cardiopulmonary bypass for cardiac surgery, and demonstrate that the incidence of postoperative infections is significantly lower in patients ventilated during cardiopulmonary bypass.

Conditions

  • Cardiopulmonary Bypass

Interventions

DEVICE

Maintaining mechanical ventilation during surgery

dead space ventilation using tidal volume of 2.5 mL/kg/pbw (predicted body weight) with 5-7 cm H2O Positive end-expiratory pressure

DEVICE

Absence of mechanical ventilation during surgery

absence of mechanical ventilation (and no Positive end-expiratory pressure) by disconnecting the tracheal tube from the ventilator

Sponsors & Collaborators

  • Rennes University Hospital

    lead OTHER

Principal Investigators

  • Jean-Marc TADIE · Rennes Hospital University

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-01-10
Primary Completion
2021-07-30
Completion
2021-07-30

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03372174 on ClinicalTrials.gov