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Propofol-remifentanyl Versus Dexmedetomidine in Awake Craniotomy: Impact on Electroclinical Seizure Activity

NCT05103735 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 170

Last updated 2023-01-31

No results posted yet for this study

Summary

Awake craniotomy require a cooperative patient during resection neurosurgery phase. Anesthesiologist should guarantee analgesia, sedation, nausea and vomiting prevention, while maintaining normal vital parameters.

Neurosurgeon could be help by Intraoperative electrocorticography to maximise lesion resection and avoiding neurologic sequelae. Propofol and remifentanyl have been largely used. Dexmedetomidine represents an alternative. However little is known about the role of dexmedetomidine on Intraoperative electrocorticography.

Conditions

  • Craniotomy
  • Seizures
  • Dexmedetomidine
  • Propofol
  • Remifentanil
  • Cerebral Tumor
  • Neurophysiology

Interventions

DRUG

Propofol

awake neurosurgery under propofol-remifentanil sedation

Sponsors & Collaborators

  • Azienda Sanitaria-Universitaria Integrata di Udine

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-09-15
Primary Completion
2021-10-10
Completion
2021-10-11

Countries

  • Italy

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05103735 on ClinicalTrials.gov