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Postoperative Cognitive Dysfunction in Transsphenoidal Pituitary Surgeries

NCT06793150 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 48

Last updated 2025-01-27

No results posted yet for this study

Summary

In this study, the patients undergoing pituitary surgery in our clinic have examined in two groups. In the first group, anesthesia maintenance was provided with remifentanil and propofol infusion. In the second group, anesthesia maintenance was provided with dexmedetomidine and propofol infusion. Demographic data, vital signs during the operation, wake-up time, extubation time, and drug consumption amounts were recorded. The mini-mental test was applied preoperatively, 24 hours postoperatively, and 3 weeks postoperatively to examine whether there is a difference in cognitive dysfunction between the two groups.

Conditions

  • Cognitive Dysfunction
  • Opioid Free Anesthesia

Interventions

DRUG

Remifentanil

A comparison will be made by maintaining one group with remifentanil and the other with dexmedetomidine.

DRUG

dexmedetomidin

A comparison will be made by maintaining one group with remifentanil and the other with dexmedetomidine.

Sponsors & Collaborators

  • Kocaeli University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-09-01
Primary Completion
2024-01-31
Completion
2024-03-31

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06793150 on ClinicalTrials.gov