Simultaneous Multinuclear Metabolic MRI in Newly Diagnosed or Recurrent Glioma
NCT05045027 · Status: ACTIVE_NOT_RECRUITING · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 36
Last updated 2025-11-14
Summary
This clinical trial constructs and tests a novel multinuclear metabolic magnetic resonance imaging (MRI) sequence in patients with glioma (brain tumor) that is newly diagnosed or has come back (recurrent). This trial aims to develop new diagnostic imaging technology that may bridge gaps between early detection and diagnosis, prognosis, and treatment in brain cancer.
Conditions
- Glioma
- Malignant Glioma
- Recurrent Glioma
- Recurrent Malignant Glioma
Interventions
- PROCEDURE
-
Biospecimen Collection
Undergo collection of tissue samples
- PROCEDURE
-
Diagnostic Imaging
Undergo multinuclear metabolic imaging
- PROCEDURE
-
Magnetic Resonance Imaging
Undergo MRI
Sponsors & Collaborators
-
United States Department of Defense
collaborator FED -
Jonsson Comprehensive Cancer Center
lead OTHER
Principal Investigators
-
Benjamin M Ellingson · UCLA / Jonsson Comprehensive Cancer Center
Study Design
- Allocation
- NA
- Purpose
- BASIC_SCIENCE
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2021-09-01
- Primary Completion
- 2026-09-10
- Completion
- 2027-09-10
- FDA Device
- Yes
Countries
- United States
Study Locations
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