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Tumor DNA and MRI/CT Scan Findings in Patients With Grade III or Grade IV Malignant Glioma

NCT00897611 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 42

Last updated 2012-11-30

No results posted yet for this study

Summary

RATIONALE: Studying levels of tumor DNA in the samples of blood from patients with cancer may help doctors find out whether the cancer has grown and how much.

PURPOSE: This laboratory study is comparing levels of tumor DNA with MRI and CT scan findings to measure cancer growth in patients with grade III or grade IV malignant glioma.

Conditions

Interventions

PROCEDURE

DNA methylation analysis

PROCEDURE

polymerase chain reaction

PROCEDURE

computed tomography

PROCEDURE

magnetic resonance imaging

Sponsors & Collaborators

  • National Cancer Institute (NCI)

    collaborator NIH

  • North American Brain Tumor Consortium

    collaborator OTHER

  • Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

    lead OTHER

Principal Investigators

  • Stuart A. Grossman, MD · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

  • Kyle Weaver, MD · Vanderbilt-Ingram Cancer Center

Study Design

Allocation
NA
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2005-04-30
Primary Completion
2009-08-31

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00897611 on ClinicalTrials.gov