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The Effects of Dietary Supplementation on Serum Protein Glycosylation

NCT05040204 · Status: RECRUITING · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 44

Last updated 2025-12-02

No results posted yet for this study

Summary

Two randomized double-blind placebo-controlled clinical studies to assess the effects of dietary glycan monomer supplementation on the immune system, especially antibody glycosylation in healthy adults. Immune profiling and glycoproteomics will be performed on serum isolated at these same time points.

Conditions

  • Healthy

Interventions

DIETARY_SUPPLEMENT

Monosaccharide Powder

Monosaccharide powder dissolved in water.

DIETARY_SUPPLEMENT

Placebo Comparator

Placebo (glucose powder)

Sponsors & Collaborators

  • National Institutes of Health (NIH)

    collaborator NIH

  • National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

    collaborator NIH

  • University of California, Davis

    lead OTHER

Principal Investigators

  • Emanual Maverakis, MD · University of California, Davis

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2022-06-23
Primary Completion
2026-05-01
Completion
2026-09-01

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05040204 on ClinicalTrials.gov