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Releasing of Inflammatory Mediators During Retreatment of Root Canals

NCT05039502 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 75

Last updated 2021-09-09

No results posted yet for this study

Summary

Nonsurgical root canal retreatment may become essential when the initial endodontic treatment fails because of the persistent intracanal or extracanal infections.The aim of this thesis study is to evaluate the effect of ProTaper Universal Retreatment (PTUR), Reciproc blue and XP-endo Finisher R file systems, which are used in the removal of root canal filling materials during retreatment with different motion kinetics on the release of Substance P, Calcitonin Gene-Related Peptide (CGRP), IL-6 and IL-10 inflammatory mediators in the periapical region

Conditions

  • Inflammatory Response
  • Root Canal Infection

Interventions

OTHER

Protaper Universal Retreatment

D1-D2-D3 Retreatment files were used in 500 rpm and 3 Ncm with X-Smart endomotor

OTHER

Reciproc

R25 retratment files were used with X-Smart endomotor in reciprocal motion

OTHER

XP-Endo finisher R

XP-Endo finisher r file were used in 1000 rpm 1 Ncm with X-Smart endomotor

Sponsors & Collaborators

  • Bulent Ecevit University

    lead OTHER

Principal Investigators

  • Sevinç Aktemur Türker · Bulent Ecevit University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
68 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2020-10-01
Primary Completion
2021-03-15
Completion
2021-06-01

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05039502 on ClinicalTrials.gov