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Chronic Pain in Rheumatoid Arthritis

NCT05038553 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 125

Last updated 2025-04-29

No results posted yet for this study

Summary

The objective is to identify modifiable clinical factors and neurobiological pathways that lead to the development of chronic pain in patients with early rheumatoid arthritis. Participants will undergo quantitative sensory testing, a type of testing that involves assessing response to well-defined, quantifiable painful stimuli, at 0, 3, and 12 months. A subset of participants will also undergo magnetic resonance imaging at 0 and 12 months to assess neuroimaging markers that have previously been shown to be involved in chronic pain.

Conditions

  • Arthritis, Rheumatoid
  • Pain

Interventions

OTHER

No intervention

No intervention

Sponsors & Collaborators

Principal Investigators

  • Yvonne C Lee, MD, MMSc · Northwestern University

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-10-12
Primary Completion
2026-04-30
Completion
2026-04-30

Countries

  • United States

Study Locations

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Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05038553 on ClinicalTrials.gov