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Open Label Placebo to Reduce Prescription Opioid Use

NCT05014230 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 155

Last updated 2023-02-22

No results posted yet for this study

Summary

The goal of the proposed study is to examine the efficacy of using an honest placebo to relieve pain for patients with an acute pain condition. People with acute pain will receive their standard dose of opioid medication for pain management. In addition, some people will be asked to take placebo pills, honestly described as placebos, as well. Patients will answer a few short questions over the phone once per day for seven days about pain and opioid use. The investigators hypothesize that participants in the open label placebo group will take fewer opioids and have less pain than those in the treatment as usual group.

Conditions

  • Acute Pain

Interventions

DIETARY_SUPPLEMENT

Open Placebo

Zeebo

OTHER

Opioid medication as part of standard care

Opioid medication as prescribed by prescriber. This is not impacted by being in the research study.

Sponsors & Collaborators

  • National Institute on Drug Abuse (NIDA)

    collaborator NIH

  • The Miriam Hospital

    collaborator OTHER

  • Rhode Island Hospital

    collaborator OTHER

  • Brown University

    lead OTHER

Principal Investigators

  • Michael H Bernstein, PhD · Brown University

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-12-09
Primary Completion
2024-02-01
Completion
2024-02-01

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05014230 on ClinicalTrials.gov