Long-Term Opioid Therapy in Chronic Non-Cancer Pain: Risks and Benefits
NCT06063902 · Status: ENROLLING_BY_INVITATION · Type: OBSERVATIONAL · Enrollment: 1000
Last updated 2023-10-03
Summary
The study investigates long-term opioid treatment in patients with chronic non-cancer pain (CNCP). The study aims to prospectively identify predictive factors for work ability and for developing opioid use disorder (according to DSM-5) as well as predictive factors for pain, activity, and health-related quality of life.
It is hypothesized that certain biopsychosocial factors mapped in this study predict patterns of opioid use and the risk for developing OUD for patients with CNCP on long-term opioid therapy. Further, it is hypothesized that certain biopsychosocial factors mapped in this study predict the chance of improved work ability and other treatment benefits of long term opioid therapy in patients with CNCP.
Conditions
- Chronic Non-Cancer Pain
- Opioid Use Disorder
Sponsors & Collaborators
-
Uppsala University
lead OTHER
Principal Investigators
-
Pernilla Åsenlöf, Professor · Uppsala University
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2019-01-14
- Primary Completion
- 2027-01-14
- Completion
- 2027-01-14
Countries
- Sweden
Study Locations
More Related Trials
-
The Effects of Opioid Taper on Opioid-Induced Hyperalgesia
NCT03063905 ·Status: TERMINATED
-
A Study to Evaluate Unintended Prolonged Opioid Use
NCT04024397 ·Status: COMPLETED
-
Sensory Outcomes in Active Substance Users
NCT06639438 ·Status: RECRUITING
-
Ability of Aprepitant to Block Opioid Reward in Non-Dependent Opiate Abusers
NCT00726960 ·Status: UNKNOWN ·Phase: PHASE1
-
Effects of Environmental Factors on Opiate Drug Choice in Opioid Dependent Individuals.
NCT00608504 ·Status: COMPLETED
-
Tapering From Long-term Opioid Therapy in Chronic Pain Population. Randomized Controlled Trial With 12 Months Follow up
NCT03485430 ·Status: COMPLETED ·Phase: NA
-
Connected Health to Decrease Opioid Use in Patients With Chronic Pain
NCT04013529 ·Status: COMPLETED ·Phase: NA
-
Predictive Markers of the Effects of Opioid Therapy
NCT02308306 ·Status: COMPLETED
-
Oxycodone User Registry (OUR)
NCT00978328 ·Status: COMPLETED
-
POINT - Preventing an Opioid Epidemic in Norway: Focusing on Treatment of Chronic Pain
NCT05828121 ·Status: UNKNOWN ·Phase: NA
-
Medicinal Dependence and Chronic Pain: Addictive Evaluation in CETD
NCT03635346 ·Status: COMPLETED
-
Buprenorphine for Cancer Pain
NCT05910190 ·Status: UNKNOWN ·Phase: PHASE4
-
Subdissociative Dose Ketamine for Treatment of Acute Pain in Subjects With Chronic Pain
NCT02920528 ·Status: COMPLETED ·Phase: PHASE3
-
Evaluation of a Compliance Marker in Prescription Opioid Abusers With Chronic Pain
NCT02276989 ·Status: WITHDRAWN ·Phase: PHASE2
-
Effect of Standard of Care Reduced Dose Versus Full Dose Buprenorphine/Naloxone in the Perioperative Period on Pain Control and Post-Operative Opioid Use Disorder Symptoms
NCT04091009 ·Status: WITHDRAWN ·Phase: PHASE4
-
Evaluation of a Health Plan Initiative to Mitigate Chronic Opioid Therapy Risks
NCT02224508 ·Status: COMPLETED
-
Neuroimaging of Opioid Phase (OPAL)
NCT05905419 ·Status: RECRUITING ·Phase: NA
-
Aprepitant Effects on Oxycodone Response
NCT00999544 ·Status: COMPLETED ·Phase: NA
-
Epidural Methadone in Healthy Volunteers
NCT03525509 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Pilot Trial of Opioid Taper Support
NCT01883882 ·Status: COMPLETED ·Phase: NA
-
Incidence and Predictors of Opioid Overdose and Death Among Long-Term Users of Opioid Analgesics
NCT02662153 ·Status: COMPLETED
-
Prescription Opioid Effects in Abusers Versus Non-Abusers
NCT00158184 ·Status: COMPLETED ·Phase: PHASE2
-
Developing Brain Stimulation as a Treatment for Chronic Pain in Opiate Dependent
NCT03681769 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Buprenorphine Combination Tablet Feasibility - 1
NCT00000298 ·Status: COMPLETED ·Phase: PHASE2
-
Project 1 Aim 2, Adaptations of the Brain in Chronic Pain With Opioid Exposure
NCT05463367 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2